Recent Publications in Women’s Mental Health

Lee H, Koh JW, Kim YA, Chun KC, Han JY, Hwang JH, Choi JS, Joo SH, Kwon HY. Entrance Pharmacol. 2022 Apr 25;13:854562.

In a potential research of alprazolam-exposed (N = 96) and non-exposed (N = 629) ladies, use of alprazolam was related to the next outcomes: spontaneous abortion (OR = 2.38; 95% CI 1.20-4.69), LBW (OR = 3.65; 95% CI 1.22-11.00), and Apgar rating at 1 min ? 7 (OR = 2.19; 95% CI 1.02-4.67). There was no important distinction in congenital abnormalities between the publicity and non-exposure teams.

Hypnotic Benzodiazepine Receptor Agonist exposure during pregnancy and the risk of congenital malformations and other adverse pregnancy outcomes: A systematic review and meta-analysis.

Grigoriadis S, Alibrahim A, Mansfield JK, Sullovey A, Robinson GE. Acta Psychiatr Scand. 2022 Apr 29.

5 research have been pooled to judge danger of congenital malformations following first trimester publicity; there was no statistically important affiliation (OR 0.87, 95% CI 0.56-1.36).

Prenatal exposure to benzodiazepines and Z-drugs in humans and risk of adverse neurodevelopmental outcomes in offspring: A systematic review.

Wang X, Zhang T, Ekheden I, Chang Z, Hellner C, Jan Hasselström, Jayaram-Lindström N, M D’Onofrio B, Larsson H, Mataix-Cols D, Sidorchuk A. Neurosci Biobehav Rev. 2022 Apr 1;137:104647.

Because of the inconsistencies throughout research, it was not attainable to achieve a conclusion.

First-trimester exposure to benzodiazepines and risk of congenital malformations in offspring: A population-based cohort study in South Korea.

Noh Y, Lee H, Choi A, Kwon JS, Choe SA, Chae J, Kim DS, Shin JY. PLoS Med. 2022 Mar 2;19(3):e1003945. Free PMC article.

Amongst a complete of three,094,227 pregnancies, 40,846 (1.3%) have been uncovered to benzodiazepines in the course of the first trimester. The adjusted RR was 1.09 (95% CI 1.05 to 1.13, p < 0.001) for general danger of malformations and 1.15 (1.10 to 1.21, p < 0.001) for coronary heart defects.

Antipsychotic Use During Pregnancy and Risk for Gestational Diabetes: A National Register-Based Cohort Study in Sweden.

Heinonen E, Forsberg L, Nörby U, Broad Ok, Källén Ok. CNS Medication. 2022 Might;36(5):529-539.

The adjusted danger ratio for gestational diabetes for ladies handled with high-risk metabolic second-generation antipsychotics throughout being pregnant was 1.8 (95% CI 1.3-2.4) in comparison with untreated ladies. Different antipsychotics weren’t related to metabolic dangers.

Prenatal exposure to benzodiazepines and the development of the offspring – a systematic review.

Jensen AG, Knudsen SS, Bech BH. Neurotoxicol Teratol. 2022 Feb 18;91:107078.

Prenatal publicity to benzodiazepines was related to worse neurodevelopmental outcomes; nevertheless, outcomes have been contradicting, and it can’t be dominated out that the findings is perhaps because of bias.

Bilal AM, Fransson E, Bränn E, Eriksson A, Zhong M, Gidén Ok, Elofsson U, Axfors C, Skalkidou A, Papadopoulos FC. BMJ Open. 2022 Apr 27;12(4):e059033. Free PMC article.

The Mom2B smartphone app will probably be examined in 5000 Swedish ladies. Energetic information assortment consists of surveys associated to participant background data, psychological and bodily well being, life-style, and social circumstances, in addition to voice recordings. Contributors’ normal smartphone exercise, geographical motion patterns, social media exercise and cognitive patterns will be estimated via passive information assortment from smartphone sensors and exercise logs.

A comparison of symptoms of bipolar and unipolar depression in postpartum women.

Clark CT, Sit DK, Zumpf KB, Ciolino JD, Yang A, Fisher SD, Wisner KL. J Have an effect on Disord. 2022 Apr 15;303:82-90.

Measurement and conceptualization of maternal PTSD following childbirth: Psychometric properties of the City Birth Trauma Scale-French Version (City BiTS-F).

Sandoz V, Hingray C, Stuijfzand S, Lacroix A, El Hage W, Horsch A. Psychol Trauma. 2022 Might;14(4):696-704.

A single intravenous administration of a sub-anesthetic ketamine dose during the perioperative period of cesarean section for preventing postpartum depression: A meta-analysis.

Li Q, Wang S, Mei X. Psychiatry Res. 2022 Apr;310:114396.

Meta-analysis confirmed that in ketamine group, the rating and the prevalence of PPD inside 1 week postpartum have been considerably decreased, whereas PPD rating after 4 weeks postpartum confirmed no superiority.

Comparison of Estimated Incentives for Preventing Postpartum Depression in Value-Based Payment Models Using the Net Present Value of Care vs Total Cost of Care.

Counts NZ, Kuklinski MR, Wong V, Feinberg ME, Creedon TB. JAMA Netw Open. 2022 Apr 1;5(4):e229401. Free PMC article.

Offering preventive interventions for postpartum melancholy resulted in an estimated 5-year financial savings of $734.12) per individual. With out medical insurance churn, sharing 50% of 5-year anticipated financial savings might supply greater than double the monetary incentives for clinicians to stop postpartum melancholy in contrast with conventional value-based cost (VBP, $367.06 vs $177.74, respectively), with a excessive probability of optimistic return for the well being care payer (91%).

Hirschtritt ME, Avalos LA, Sarovar V, Ridout KK, Goler NC, Ansley DR, Satre DD, Younger-Wolff KC. J Addict Med. 2022 Jan 11.

Impact of prenatal tobacco smoking on infant telomere length trajectory and ADHD symptoms at 18?months: a longitudinal cohort study.

Howell MP, Jones CW, Herman CA, Mayne CV, Fernandez C, Theall KP, Esteves KC, Drury SS. BMC Med. 2022 Apr 28;20(1):153. Free PMC article.

In line with earlier cross-sectional research linking shorter offspring TL to maternal prenatal smoking, maternal prenatal smoking predicted higher telomere shortening from 4 to 18 months of toddler age. Maternal melancholy was positively related to each prenatal smoking (odds ratio (OR): 4.614, 95% CI [1.733, 12.282]; p = 0.002) and baby ADHD signs (? = 4.713, 95% CI [2.073, 7.354]; p = 0.0006).

Wu Y, Espinosa KM, Barnett SD, Kapse A, Quistorff JL, Lopez C, Andescavage N, Pradhan S, Lu YC, Kapse Ok, Henderson D, Vezina G, Wessel D, du Plessis AJ, Limperopoulos C. JAMA Netw Open. 2022 Apr 1;5(4):e229244. Free PMC article.

Altered prenatal mind improvement within the setting of elevated maternal misery has hostile toddler sociocognitive outcomes. Figuring out early biomarkers related to long-term neurodevelopment might help in early focused interventions.