Introduction
I’ve had a basic article on the checklist to overview for a while. It’s referred to as “Paradox of hypercholesterolaemia in extremely educated, keto-adapted athletes” and Creighton was the lead creator (Ref 1). Readers of the Monday notice could also be extra acquainted with the names of two different authors: Professors Stephen Phinney and Jeff Volek. Phinney and Volek are the authors of a few classics within the area of low carbohydrate literature: The Artwork & Science of Low Carbohydrate Dwelling (2011) and The Artwork & Science of Low Carbohydrate Efficiency (2012).
The Creighton et al article was the primary (of which I used to be conscious), which tried to handle the paradox (as they referred to as it) of excessive ldl cholesterol and low-carbohydrate diets. Some folks discover that their ldl cholesterol measurements (complete and LDL-cholesterol particularly) improve markedly once they undertake a low-carb weight-reduction plan. These folks then face a tough choice, as they’re usually valuing the advantages of the low-carb weight-reduction plan, however they see the ldl cholesterol change as a major draw back. Many report that their medical doctors and cardiologists (if they’ve one) turn into very involved and it’s then harder to proceed with the low-carb weight-reduction plan.
In November 2021, Might 2022 and August 2022, three different articles on this matter have been revealed together with authors probably recognized to you.
1) November 2021: Norwitz et al. Elevated LDL Ldl cholesterol with a Carbohydrate-Restricted Eating regimen: Proof for a “Lean Mass Hyper-Responder” Phenotype (Ref 2). (Authors you could know on this workforce embody David Ludwig and Dave Feldman).
2) Might 2022: Norwitz et al. The Lipid Vitality Mannequin: Reimagining Lipoprotein Perform within the Context of Carbohydrate-Restricted Diets. (This paper additionally options David Ludwig and Dave Feldman as authors) (Ref 3).
3) August 2022: Diamond et al. Statin remedy just isn’t warranted for an individual with excessive LDL-cholesterol on a low-carbohydrate weight-reduction plan (Ref 4). (You might recognise Ben Bikman and Paul Mason as co-authors).
This can be a matter of curiosity to many individuals who restrict their carbohydrate consumption and/or go so far as keto or carnivore diets, so I’ll cowl the Creighton et al and the primary Norwitz et al papers this week. I’ll have a look at the second Norwitz et al paper, on the Lipid Vitality Mannequin, subsequent week. The Diamond et al paper is on the checklist for a potential future Monday notice.
