Introduction
In 2021, Ludwig et al revealed a perspective paper referred to as “The carbohydrate-insulin mannequin: a physiological perspective on the weight problems pandemic” (Ref 1). I did a Monday observe on this paper on the time (Ref 2). In Could 2022, Corridor et al revealed a response to the Ludwig et al paper referred to as “The power stability mannequin of weight problems: past energy in, energy out” (Ref 3). Ludwig et al have simply revealed their response to Corridor et al’s article referred to as “Competing paradigms of weight problems pathogenesis: power stability versus carbohydrate-insulin fashions” (Ref 4). This might go on for some time.
The continued debate is about the reason for weight problems. The 2 positions may be summarised as an power stability mannequin (abbreviated to EBM) and a carbohydrate-insulin mannequin (abbreviated to CIM). The talk boils all the way down to those that consider that weight problems is the results of an power imbalance – an excessive amount of power in and/or too little power expended – and those that consider what has turn into often known as “the carbohydrate-insulin mannequin of weight problems.” The latter may be summarised because the view “that hormonal responses to extremely processed carbohydrates shift power partitioning towards deposition in adipose tissue, leaving fewer energy out there for the physique’s metabolic wants.”
Final week I summarised the important thing factors from the Corridor et al paper. (Look again on the govt abstract in the event you’d like a reminder) (Ref 5). This week we’re trying on the Ludwig et al reply and my views on the trade.
